The FDA has approved investigational new drug applications and granted fast track status to several therapies, including LP-184 for triple-negative breast cancer. Early data from clinical trials indicate promising results for novel treatments targeting difficult-to-treat cancers such as melanoma and myeloma.
Pope Leo XIV has become the first US-born leader of the Roman Catholic Church, and his diverse family background highlights America's complex history with race and immigration. His election is seen as a reflection of the changing face of Catholicism and the global influence of the United States.
The United States and Iran have commenced a fourth round of negotiations in Oman focused on Iran’s nuclear program. The discussions aim to resolve significant disagreements that threaten to derail ongoing diplomatic efforts.
Recent research suggests that complex intelligence, as seen in birds and mammals, evolved independently in these two groups. This challenges the notion that intelligence is a unique or linear evolutionary development among vertebrates, and provides new insights into how sophisticated neural circuits, such as those found in the human brain, may have arisen.
Israeli airstrikes killed at least 23 Palestinians in Gaza, including three children and their parents, as international criticism mounts over Israel's blockade of humanitarian aid to the territory.
Shortly after a ceasefire agreement was announced between India and Pakistan, explosions were reported in Srinagar, Kashmir. Both countries have accused each other of violating the truce, with reports of drone attacks continuing in the region. Experts suggest that mutual claims of victory could help stabilize the ongoing crisis.
A large-scale search and rescue operation is ongoing in Buncrana, County Donegal, after reports that several children encountered difficulties while swimming in Lough Swilly. Emergency services, including a helicopter, lifeboats, and ambulances, are at the scene amid concerns that some children may be missing or drowned.
AI companies are being called upon to conduct rigorous safety assessments—similar to those performed before the first nuclear test—to evaluate the existential risks posed by advanced artificial intelligence. Max Tegmark, a prominent AI safety advocate, warns that without such calculations, there is a danger that superintelligent systems could escape human control.
Military tensions between India and Pakistan have escalated sharply, with India launching precision strikes on Pakistani air bases and infrastructure following a series of projectile and fighter attacks by Pakistan. The exchanges have targeted both military and civilian sites, raising concerns about further escalation.
The leaders of Britain, France, Germany, and Poland, together with Ukrainian President Volodymyr Zelensky, have proposed an unconditional 30-day ceasefire in the Ukraine war. The proposal was discussed in a phone call with US President Donald Trump.